Nekhaev A S, Degtiarev V A, Bednenko V S, Kirillova Z A
Kosm Biol Aviakosm Med. 1982 Sep-Oct;16(5):54-7.
Venous and arterial circulation was investigated by simulating cephalad blood shifts generated by an exposure of test subjects (n = 15) to lower body positive pressure (+25 mm Hg) and head-down tilts (at -8 degrees and -15 degrees). At LBPP and tilt -15 degrees arterial pressure increased by 5-15%. During tilt -8 degrees jugular vein blood filling increased by 8-94% in the course of the first 3 hrs and then decreased reaching the baseline (horizontal position) level. During LBPP the parameter changed in a similar manner (increased by 2-50%). During tilt -15 degrees the parameter grew by 10-110% and remained elevated. The exposures gave rise to bradycardia which was more pronounced during -8 degrees and LBPP. The data obtained give evidence that circulation changes during LBPP and head-down tilts are identical. This suggests that LBPP can be used to simulate the effect of cephalad blood shifts, one of the most important effects of weightlessness on the human body.
通过模拟受试者（n = 15）暴露于下体正压（+25 mmHg）和头低位倾斜（-8度和-15度）所产生的头向血液转移，对静脉和动脉循环进行了研究。在下体正压和-15度倾斜时，动脉压升高了5% - 15%。在-8度倾斜时，颈静脉血液充盈在前3小时内增加了8% - 94%，然后下降至基线（水平位）水平。在下体正压期间，该参数以类似方式变化（增加2% - 50%）。在-15度倾斜时，该参数增加了10% - 110%并保持升高。这些暴露引起了心动过缓，在-8度和下体正压时更为明显。所获得的数据表明，下体正压和头低位倾斜期间的循环变化是相同的。这表明下体正压可用于模拟头向血液转移的效应，这是失重对人体最重要的效应之一。
