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Alkylation-induced sister-chromatid exchanges correlate with reduced cell survival, not mutations.

作者信息

Morris S M, Heflich R H, Beranek D T, Kodell R L

出版信息

Mutat Res. 1982 Sep;105(3):163-8. doi: 10.1016/0165-7992(82)90006-9.

DOI:10.1016/0165-7992(82)90006-9
PMID:7144786
Abstract
摘要

相似文献

1
Alkylation-induced sister-chromatid exchanges correlate with reduced cell survival, not mutations.烷基化诱导的姐妹染色单体交换与细胞存活率降低相关,而非与突变相关。
Mutat Res. 1982 Sep;105(3):163-8. doi: 10.1016/0165-7992(82)90006-9.
2
Induction of chromosomes aberrations, sister chromatid exchanges, and specific locus mutations in Chinese hamster ovary cells by 5-bromodeoxyuridine.5-溴脱氧尿苷对中国仓鼠卵巢细胞染色体畸变、姐妹染色单体交换及特定位点突变的诱导作用
Cytogenet Cell Genet. 1980;28(1-2):47-54. doi: 10.1159/000131511.
3
[Characteristics of sister chromatid exchange induction by short exposures to chemical mutagens].
Dokl Akad Nauk SSSR. 1983 Nov-Dec;273(1):221-3.
4
Sister-chromatid exchanges but not mutations decrease with time in arrested Chinese hamster ovary cells after treatment with ethylnitrosourea.在用乙基亚硝基脲处理后,处于停滞状态的中国仓鼠卵巢细胞中,姐妹染色单体交换而非突变随时间减少。
Mutat Res. 1981 Jul-Sep;91(4-5):371-5. doi: 10.1016/0165-7992(81)90017-8.
5
Sister chromatid exchange and gene mutation.姐妹染色单体交换与基因突变。
Cytogenet Cell Genet. 1982;33(1-2):57-61. doi: 10.1159/000131726.
6
[Relation of the effectiveness of inducing sister chromatid exchanges to the chemical structure of the mutagen].
Genetika. 1982 Feb;18(2):269-74.
7
Gene mutation and sister chromatid exchange in Chinese hamster cells.中国仓鼠细胞中的基因突变与姐妹染色单体交换
Acta Biol Acad Sci Hung. 1979;30(4):355-61.
8
Mutagenic responses of thirteen anticancer drugs on mutation induction at multiple genetic loci and on sister chromatid exchanges in Chinese hamster ovary cells.13种抗癌药物对中国仓鼠卵巢细胞多个基因位点突变诱导及姐妹染色单体交换的诱变反应。
Cancer Res. 1983 Feb;43(2):577-84.
9
Sister chromatid exchange assays: pre-scanning of chemicals for subtoxic levels.姐妹染色单体交换试验:对化学物质进行亚毒性水平的预筛选。
Med Lab Sci. 1981 Mar;38(2):117-9.
10
DNA crosslinking, sister-chromatid exchange and specific-locus mutations.
Mutat Res. 1979 Nov;63(1):175-88. doi: 10.1016/0027-5107(79)90114-3.

引用本文的文献

1
Blocked 5'-termini in the fragments of chromosomal DNA produced in cells exposed to the antitumor drug 4'-[(9-acridinyl)-amino]methanesulphon-m-anisidide (mAMSA).暴露于抗肿瘤药物4'-[(9-吖啶基)-氨基]甲磺基间茴香胺(mAMSA)的细胞中产生的染色体DNA片段的5'-末端被封闭。
Nucleic Acids Res. 1983 Jun 25;11(12):4251-6. doi: 10.1093/nar/11.12.4251.
2
Repair of O6-(2-chloroethyl)guanine mediates the biological effects of chloroethylnitrosoureas.O6-(2-氯乙基)鸟嘌呤的修复介导了氯乙基亚硝脲的生物学效应。
Environ Health Perspect. 1985 Oct;62:119-26. doi: 10.1289/ehp.8562119.
3
Sister chromatid exchange frequency, cellular replication and relative cloning efficiency in human teratocarcinoma-derived cells.
Cell Biol Toxicol. 1988 Sep;4(3):281-94. doi: 10.1007/BF00058737.
4
Structure/activity investigations in eight arylalkyltriazenes comparison of chemical stability, mode of decomposition, and SCE induction in Chinese hamster V79-E cells.八种芳基烷基三氮烯的结构/活性研究:中国仓鼠V79-E细胞中化学稳定性、分解模式及姐妹染色单体互换诱导的比较
Cell Biol Toxicol. 1991 Apr;7(2):145-65. doi: 10.1007/BF00122828.