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[后颅窝肿瘤所致脑积水患者睡眠分析相关脑脊液压力变化的临床理论方面]

[Clinico-theoretical aspects of cerebrospinal fluid pressure changes associated with sleep analysis in patients with hydrocephalus caused by posterior fossa tumors].

作者信息

Smyk K, Darwaj B, Koźniewska H, Muszyński A, Czochra T

出版信息

Neurol Neurochir Pol. 1982 Jul-Aug;16(4):273-80.

PMID:7145015
Abstract

In 6 patients treated for hydrocephalus caused by posterior fossa tumours simultaneous continuous measurement of intraventricular cerebrospinal fluid pressure and all-night polygraphic sleep recording were carried out before and after implantation of ventriculoatrial valve. It was observed that in patients with hydrocephalus and raised CSF pressure electrography demonstrated a breakdown of the cyclic sleep pattern with increased duration of light sleep and higher number of awakening episodes, and with reduced amount of deep sleep and nearly complete absence of REM sleep. The degree of sleep disturbances seemed to be correlated with increased value of CSF pressure. In that period discrepancies were observed between the sleep record suggesting waking and the behaviour of the patient who was asleep at that time. With normalization of CSF pressure record (after valve implantation) an improvement of sleep pattern was observed which approached the normal one.

摘要

对6例因后颅窝肿瘤导致脑积水而接受治疗的患者,在植入脑室心房分流管前后,同时进行了脑室内脑脊液压力的连续测量以及整夜多导睡眠记录。观察到,在脑积水且脑脊液压力升高的患者中,脑电图显示周期性睡眠模式被打破,浅睡眠持续时间增加,觉醒次数增多,深睡眠量减少,快速眼动睡眠几乎完全缺失。睡眠障碍的程度似乎与脑脊液压力值升高相关。在那段时间里,睡眠记录提示清醒,但当时患者实际处于睡眠状态,二者之间存在差异。随着脑脊液压力记录恢复正常(瓣膜植入后),睡眠模式得到改善,接近正常水平。

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