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Micro-ELISA for detecting and assaying snake venom and venom-antibody.

作者信息

Theakston R D, Lloyd-Jones M J, Reid H A

出版信息

Lancet. 1977 Sep 24;2(8039):639-41. doi: 10.1016/s0140-6736(77)92502-8.

DOI:10.1016/s0140-6736(77)92502-8
PMID:71452
Abstract

Enzyme-linked immunosorbent assay (ELISA) can detect venom levels down to 1-5 ng/ml. The assay is specific; no cross-reaction of clinical importance was found in a range of 14 different types of venom. Both venom and venom-antibody levels were monitored in mice. Specific antibody was detected in human serum more than 2 years after an accidental bite by Echis carinatus. ELISA should clarify many basic problems of envenoming in man.

摘要

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