Sisk C L, Stephan F K
Physiol Behav. 1982 Aug;29(2):231-9. doi: 10.1016/0031-9384(82)90009-9.
The role of the central visual pathways in determining the distribution of sleep in light-dark (LD) cycles in the circadian and ultradian range was examined. EEG, EMG, and brain temperature were recorded under 24-hr (LD 12:12 or LD 10:14) and 1-hr (LD 0.5:0.5) cycles in rats which received either (1) no lesion, (2) primary optic tract lesions, (3) lesions of dorsal and lateral terminal nuclei of the accessory optic system, (4) lesions of medial terminal nucleus of the accessory optic system, or (5) retinohypothalamic tract-suprachiasmatic nucleus lesions. Under 24-hr cycles, about 40% of sleep occurred in the dark in intact rats. Retinohypothalamic tract-suprachiasmatic nucleus lesions abolished this entrainment of sleep to the LD cycle. Under 1-hr cycles, 90% of REM sleep occurred in the dark periods in intact rats. While primary optic tract lesions attenuated this response, it was not completely abolished by any of the visual system lesions. The characteristic LD distributions of sleep in circadian and ultradian cycles may therefore be under separate neural control by the central visual system.
研究了中枢视觉通路在昼夜节律和超昼夜范围内的明暗（LD）周期中决定睡眠分布的作用。在24小时（LD 12:12或LD 10:14）和1小时（LD 0.5:0.5）周期下，记录接受以下处理的大鼠的脑电图（EEG）、肌电图（EMG）和脑温：（1）无损伤；（2）原发性视束损伤；（3）副视系统背侧和外侧终核损伤；（4）副视系统内侧终核损伤；或（5）视网膜下丘脑束-视交叉上核损伤。在24小时周期下，完整大鼠约40%的睡眠发生在黑暗期。视网膜下丘脑束-视交叉上核损伤消除了睡眠对LD周期的这种同步。在1小时周期下，完整大鼠90%的快速眼动睡眠发生在黑暗期。虽然原发性视束损伤减弱了这种反应，但任何视觉系统损伤都没有完全消除它。因此，昼夜节律和超昼夜周期中睡眠的特征性LD分布可能受中枢视觉系统的不同神经控制。
