Austad E D, Pasyk K A, McClatchey K D, Cherry G W
Plast Reconstr Surg. 1982 Dec;70(6):704-10. doi: 10.1097/00006534-198212000-00008.
To evaluate the histologic changes attendant on tissue expansion in the guinea pig, self-inflating implants were placed in the dorsal subcutaneous space and the tissue response was sequentially studied at periods ranging from 1 to 18 weeks. Fixation artifacts have been minimized. The cellular response is relatively benign. The epidermis does not undergo thinning during expansion, although dermis and panniculus carnosus become significantly thinner. Atrophy of panniculus muscle is demonstrable. This study supports the hypothesis that tissue expansion results in a net gain of donor tissue.
为评估豚鼠组织扩张时伴随的组织学变化，将自膨胀植入物置于背部皮下间隙，并在1至18周的时间段内依次研究组织反应。固定伪像已减至最小。细胞反应相对良性。在扩张过程中表皮未变薄，尽管真皮和 panniculus carnosus（此处可能是指“浅筋膜”，具体需结合专业知识进一步确认）明显变薄。浅筋膜肌肉萎缩是可证实的。本研究支持组织扩张导致供体组织净增加这一假说。
