Bartell T H, Mustoe T A
Department of Surgery, Barnes Hospital, St. Louis, Mo.
Plast Reconstr Surg. 1989 Apr;83(4):681-6. doi: 10.1097/00006534-198904000-00014.
Although tissue expansion is being used extensively in humans, many fundamental scientific questions remain to be addressed which can best be answered using an animal model. Presently, no single animal has been identified for research of this kind which is comparable both subjectively and objectively to humans. This study evaluates the skin of the rat, guinea pig, pig, and dog and identifies the dog as the best model based on biomechanical and practical considerations.
尽管组织扩张术在人类中得到了广泛应用，但仍有许多基础科学问题有待解决，而使用动物模型能最好地回答这些问题。目前，尚未找到一种在主观和客观上都能与人类相媲美的单一动物用于此类研究。本研究评估了大鼠、豚鼠、猪和狗的皮肤，并基于生物力学和实际考虑因素确定狗是最佳模型。
