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[分离的大鼠肝细胞中酮糖引起的克氏效应]

[Crabtree effect caused by ketoses in isolated rat hepatocytes].

作者信息

Martínez P, Carrascosa J M, Núñez de Castro I

出版信息

Rev Esp Fisiol. 1982;38 Suppl:181-3.

PMID:7146574
Abstract

Oxygen uptake and glycolytic activity were studied in hepatocytes isolated from fed rats. The addition of fructose or tagatose resulted in a 38% and 31% inhibition of cellular respiration respectively. The addition of 10 mM D-glyceraldehyde caused a slight Crabtree effect. Glucose, L-sorbose, or glycerol failed to modify oxygen consumption. Only incubation in the presence of fructose showed a high aerobic glycolysis measured by lactate production.

摘要

在从喂食大鼠分离的肝细胞中研究了氧摄取和糖酵解活性。添加果糖或塔格糖分别导致细胞呼吸抑制38%和31%。添加10 mM D-甘油醛引起轻微的克氏效应。葡萄糖、L-山梨糖或甘油未能改变氧消耗。只有在果糖存在下孵育时,通过乳酸生成测量显示出高需氧糖酵解。

相似文献

1
[Crabtree effect caused by ketoses in isolated rat hepatocytes].[分离的大鼠肝细胞中酮糖引起的克氏效应]
Rev Esp Fisiol. 1982;38 Suppl:181-3.
2
Ketose induced respiratory inhibition in isolated hepatocytes.酮糖在分离的肝细胞中诱导呼吸抑制。
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Crabtree effect induced by fructose in hepatocytes isolated from regenerating liver.再生肝分离的肝细胞中果糖诱导的克奈特效应。
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The influence of fructose and its metabolites on ethanol metabolism in vitro.果糖及其代谢产物对体外乙醇代谢的影响。
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Crabtree effect induced by fructose in isolated hepatocytes from fed rats.喂食大鼠分离肝细胞中由果糖诱导的克奈特效应。
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Fructose and tagatose protect against oxidative cell injury by iron chelation.果糖和塔格糖通过铁螯合作用防止细胞氧化损伤。
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[Effect of ammonia on the Crabtree effect of 2 strains of Ehrlich ascites tumor].[氨对两株艾氏腹水瘤细胞克氏效应的影响]
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Crabtree effect induced by fructose in hepatocytes isolated from developing rats.发育中大鼠分离的肝细胞中果糖诱导的克奈特效应
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