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发育中大鼠分离的肝细胞中果糖诱导的克奈特效应

Crabtree effect induced by fructose in hepatocytes isolated from developing rats.

作者信息

Chico E, Olavarría J S, Núñez de Castro I

出版信息

Enzyme. 1979;24(3):209-11. doi: 10.1159/000458657.

DOI:10.1159/000458657
PMID:499181
Abstract

The inhibition of respiration caused by fructose is investigated in hepatocytes isolated from fetal and developing rats. The respiration rate of the hepatocytes increases in the early days after birth. Adult values for oxygen uptake are reached by hepatocytes isolated from 14-day-old rats. After weaning, the Crabtree effect induced by fructose appears simultaneously with changes in energy metabolism.

摘要

在从新生及发育中的大鼠分离出的肝细胞中研究了果糖对呼吸的抑制作用。出生后的最初几天,肝细胞的呼吸速率会增加。从14日龄大鼠分离出的肝细胞达到了成年大鼠的氧摄取值。断奶后,果糖诱导的巴斯德效应与能量代谢的变化同时出现。

相似文献

1
Crabtree effect induced by fructose in hepatocytes isolated from developing rats.发育中大鼠分离的肝细胞中果糖诱导的克奈特效应
Enzyme. 1979;24(3):209-11. doi: 10.1159/000458657.
2
Crabtree effect induced by fructose in hepatocytes isolated from regenerating liver.再生肝分离的肝细胞中果糖诱导的克奈特效应。
Enzyme. 1980;25(6):377-81. doi: 10.1159/000459285.
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[Crabtree effect caused by ketoses in isolated rat hepatocytes].[分离的大鼠肝细胞中酮糖引起的克氏效应]
Rev Esp Fisiol. 1982;38 Suppl:181-3.
4
Crabtree effect induced by fructose in isolated hepatocytes from fed rats.喂食大鼠分离肝细胞中由果糖诱导的克奈特效应。
Biochem Biophys Res Commun. 1978 Aug 29;83(4):1422-9. doi: 10.1016/0006-291x(78)91379-7.
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Ketose induced respiratory inhibition in isolated hepatocytes.酮糖在分离的肝细胞中诱导呼吸抑制。
Rev Esp Fisiol. 1987 Jun;43(2):163-71.
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Effects of fructose concentration on carbohydrate metabolism, heat production and substrate cycling in isolated rat hepatocytes.果糖浓度对分离的大鼠肝细胞碳水化合物代谢、产热及底物循环的影响
Biochem J. 1979 Dec 15;184(3):501-7. doi: 10.1042/bj1840501.
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Fasting increases the susceptibility of rat hepatocytes to the cytotoxic effects of N-hydroxy-acetylaminofluorene. Effects on mitochondrial respiration and membrane potential.禁食会增加大鼠肝细胞对N-羟基-乙酰氨基芴细胞毒性作用的敏感性。对线粒体呼吸和膜电位的影响。
Biochem Pharmacol. 1992 Dec 15;44(12):2339-45. doi: 10.1016/0006-2952(92)90678-c.
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Absorption spectrophotometry of perfused rat liver applied to fructose-induced inhibition of respiration.灌注大鼠肝脏的吸收分光光度法应用于果糖诱导的呼吸抑制研究。
Biochem Biophys Res Commun. 1970 Mar 27;38(6):1091-7. doi: 10.1016/0006-291x(70)90351-7.
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Nicotine increases hepatic oxygen uptake in the isolated perfused rat liver by inhibiting glycolysis.尼古丁通过抑制糖酵解增加离体灌注大鼠肝脏的肝氧摄取。
J Pharmacol Exp Ther. 2002 Jun;301(3):930-7. doi: 10.1124/jpet.301.3.930.
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Ammonia overloading in hepatocytes isolated from liver of fetal and adult rats.从胎鼠和成年大鼠肝脏分离的肝细胞中的氨超载
Biochim Biophys Acta. 1979 Sep 3;586(3):481-91. doi: 10.1016/0304-4165(79)90038-2.

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