Bennett F M, Tenney S M
Respir Physiol. 1982 Aug;49(2):131-40. doi: 10.1016/0034-5687(82)90069-x.
Compliances (C) of lung, thorax and respiratory system as well as resistances (R) of the respiratory system (lower airways + lung + chest wall) and of upper airway (primarily laryngeal and nasal) were measured in 5 species of mammals, spanning a 1000-fold range of body weights (mouse to dog), immediately following sacrifice with an overdose of sodium pentobarbital. The results indicate that compliance is proportional to BW1.0, while respiratory resistance and upper airway resistance have exponents of -0.819 and -0.702, respectively. The reciprocal of the time constant, tau -1 = (RC)-1 is proportional to BW-0.298 for respiratory resistance alone and BW-0.326 when upper airway resistance is included. Since breathing frequency varies as BW-0.28, these results indicate a proportional relationship between breathing frequency and passive emptying time. This suggests that passive respiratory mechanics play a major role in determining TE and therefore TTOT for animals during quiet breathing. Changes in volume history were found not to affect the slope of the relationships between compliance and body weight.
在用过量戊巴比妥钠处死5种体重范围跨越1000倍（从老鼠到狗）的哺乳动物后，立即测量了肺、胸廓和呼吸系统的顺应性（C）以及呼吸系统（下呼吸道+肺+胸壁）和上呼吸道（主要是喉部和鼻腔）的阻力（R）。结果表明，顺应性与体重的1.0次方成正比，而呼吸阻力和上呼吸道阻力的指数分别为-0.819和-0.702。时间常数的倒数，τ-1 = (RC)-1，仅对于呼吸阻力而言与体重的-0.298次方成正比，当包括上呼吸道阻力时与体重的-0.326次方成正比。由于呼吸频率随体重的-0.28次方变化，这些结果表明呼吸频率与被动排空时间之间存在比例关系。这表明被动呼吸力学在安静呼吸期间决定动物的呼气时间（TE）以及因此的总呼气时间（TTOT）方面起主要作用。发现容积历史的变化不影响顺应性与体重之间关系的斜率。
