Orbai P, Gozariu L
Endocrinologie. 1982 Jul-Sep;20(3):181-5.
The effect of triiodothyronine and thyroxine no the stimulation of the release of 45Ca was followed up in rat calvaria incubated "in vitro" and compared with the effect produced by parathormone. Both triiodothyronine and thyroxine stimulated osteolysis. The response was dependent on dose. Triiodothyronine may intensify the effect of parathormone if added to the incubation medium, whereas thyroxine does not exert the same effect. The results obtained demonstrated a well defined osteolytic effect of both thyroid hormones.
在体外培养的大鼠颅骨中，对三碘甲状腺原氨酸和甲状腺素对45Ca释放刺激的影响进行了追踪，并与甲状旁腺激素产生的影响进行了比较。三碘甲状腺原氨酸和甲状腺素均刺激骨溶解。反应取决于剂量。如果添加到孵育培养基中，三碘甲状腺原氨酸可能会增强甲状旁腺激素的作用，而甲状腺素则不会产生同样的效果。所获得的结果表明两种甲状腺激素都有明确的溶骨作用。
