Kiriakov Z, Patev E, Todorov K, Simeonov P, Dimitrova T
Vutr Boles. 1982;21(4):41-6.
Viral hepatitis has a high incidence both among patients on hemodialysis and among the attending personnel. A clinical epidemiological study on hepatitis epidemic was carried out at the department of hemodialysis--Research Institute of Nephrology, Urology, Hemodialysis and Transplantation--for an eight-year period. Twenty two per cent of the patients were affected by hepatitis infection and 27.1 per cent of the personnel. The disease has, more often, a subclinical course in the patients on hemodialysis, manifested not later than one year after the initiation of hemodialysis treatment. The epidemic of viral hepatitis a chain of five epidemic outbreaks with a considerable predomination of HBsAg--positive forms. About 15 per cent of the patients on hemodialysis are chronic carriers of HBsAg, being, very likely, associated with the altered immune reactivity. All those data support the necessity of the introduction of a campaign programme against hepatitis epidemic.
病毒性肝炎在血液透析患者及医护人员中发病率都很高。在肾病、泌尿、血液透析及移植研究所血液透析科进行了一项为期八年的肝炎流行临床流行病学研究。22%的患者受到肝炎感染,27.1%的医护人员受到感染。这种疾病在血液透析患者中往往呈亚临床病程,在开始血液透析治疗后不晚于一年出现症状。病毒性肝炎流行呈现出五起疫情爆发的链条,其中乙肝表面抗原(HBsAg)阳性形式占相当大比例。约15%的血液透析患者是HBsAg慢性携带者,很可能与免疫反应改变有关。所有这些数据都支持开展一项防治肝炎流行的活动计划的必要性。