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[用纤维蛋白粘合剂封闭胸膜和肺部病变。实验研究]

[Closure of pleura and lung lesions with fibrin adhesive. Experimental studies].

作者信息

Türk R, Weidringer J W, Wried-Lübbe I, Blümel G

出版信息

Zentralbl Chir. 1982;107(16):1016-21.

PMID:7148194
Abstract

The effect of the fibrin adhesive on the gas density of pleura-lung-sutures was investigated in 28 male Wistar rats. Standardized pleura-lung-lacerations were closed by additional fibrin adhesive application in combination with fibrinolytic inhibitors. 30 minutes and 5 days after operation the animals were sacrificed and manometric and micromorphological examinations performed. In good histo-compatibility the additional application of the fibrin adhesive proved to be a proper technique in elevating the pressure tolerance of pleura-lung-sutures significantly.

摘要

在28只雄性Wistar大鼠中研究了纤维蛋白粘合剂对胸膜-肺缝合线气体密度的影响。通过额外应用纤维蛋白粘合剂并结合纤维蛋白溶解抑制剂来闭合标准化的胸膜-肺撕裂伤。术后30分钟和5天处死动物,并进行压力测量和微观形态学检查。在良好的组织相容性方面,额外应用纤维蛋白粘合剂被证明是一种显著提高胸膜-肺缝合线耐压性的合适技术。

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