Lim D J, Dunn D E, Johnson D L, Moore T J
Acta Otolaryngol. 1982 Sep-Oct;94(3-4):213-31. doi: 10.3109/00016488209128907.
Twenty-eight chinchillas received continuous or intermittent infrasound (1, 10, 20 Hz) at 150, 160, or 170 dB SPL; there were 7 controls. Serial sections of the temporal bones were examined using light microscopy. Pathologies noted were tympanic membrane perforation, stapes subluxation, bleeding from the middle ear mucosa and tensor tympani, strial pathology, Reissner's membrane rupture, endolymphatic hydrops, saccular wall rupture, hair cell damage, and blood in the cochlear scalae. Continuous infrasound was more damaging than intermittent. Only continuous infrasound produced saccular pathology and perforations of the tympanic membrane. Of the other pathologies observed, continuous infrasound exposures produced 67% of the hair cell damage, 73% of the bleeding in the cochlear scalae, 83% of the strial pathology, and 78% of the cases of cochlear hydrops. 170-dB infrasound exposures produced the highest percentage of ears with pathologies of the three exposure intensities. As frequency increased the percentage of ears with pathologies decreased.
28只龙猫接受了150、160或170分贝声压级的连续或间歇性次声（1、10、20赫兹）；有7只作为对照。使用光学显微镜检查颞骨的连续切片。观察到的病理情况有鼓膜穿孔、镫骨半脱位、中耳黏膜和鼓膜张肌出血、螺旋器病理改变、Reissner膜破裂、内淋巴积水、球囊壁破裂、毛细胞损伤以及蜗管内出血。连续次声比间歇性次声的损害更大。只有连续次声会导致球囊病理改变和鼓膜穿孔。在观察到的其他病理情况中，连续次声暴露导致了67%的毛细胞损伤、73%的蜗管出血、83%的螺旋器病理改变以及78%的蜗管积水病例。在三种暴露强度中，170分贝的次声暴露导致耳朵出现病理改变的比例最高。随着频率增加，耳朵出现病理改变的比例下降。
