Van Dinh T, Woodruff J D
Am J Obstet Gynecol. 1982 Dec 1;144(7):817-23. doi: 10.1016/0002-9378(82)90358-1.
A series of 43 cases of uterine leiomyosarcoma was reviewed. Forty-one of the 43 patients were followed up 2 or more years. The overall 5-year survival was 73%. Favorable prognostic features included the premenopausal status of the patient, the confinement of the tumor within a myoma, the low mitotic count (less than four mitotic figures in any one high-power field or less than four mitotic figures per 10 high-power fields), the absence of necrosis, and the presence of hyalinization in the adjacent tissue suggesting confinement. Special cases such as those in which only myomectomy was performed and those receiving adjunctive chemotherapy are discussed. The differential in survival between patients with primary myosarcoma and those with lesions arising in a leiomyoma is stressed.
回顾了43例子宫平滑肌肉瘤病例。43例患者中有41例随访了2年或更长时间。总体5年生存率为73%。有利的预后特征包括患者处于绝经前状态、肿瘤局限于肌瘤内、有丝分裂计数低（任何一个高倍视野中有丝分裂象少于4个或每10个高倍视野中有丝分裂象少于4个）、无坏死以及相邻组织中有透明变性提示肿瘤局限。讨论了特殊病例，如仅行肌瘤切除术的病例以及接受辅助化疗的病例。强调了原发性平滑肌肉瘤患者与肌瘤中发生病变患者在生存率上的差异。
