Cameron D F, Snydle F E
Andrologia. 1982 Sep-Oct;14(5):425-33. doi: 10.1111/j.1439-0272.1982.tb02287.x.
Testicular biopsies were obtained from 40 otherwise healthy men with diagnosed varicocele and processed for scanning electron microscopy. Testis biopsies from two men with scrotal pain served as control. The seminiferous epithelium was variably affected, ranging from what appeared to be essentially normal to severely altered. In tubules in which normal cellular associations were compromised, the surface anatomy of the tubule epithelium was distorted, adluminal sertoli cell cytoplasm was truncated and there was an apparent displacement, reduction in number and, in some extreme cases, absence, of germ cells. Visualization of the varicocele-affected seminiferous epithelium by the scanning electron microscope reveals more fully the extent and three-dimensional character of adluminal compartment dissolution and reconfirms our four stage classification of seminiferous tubules in this pathology.
从40名被诊断患有精索静脉曲张但其他方面健康的男性身上获取睾丸活检组织，并进行扫描电子显微镜检查处理。选取两名患有阴囊疼痛的男性的睾丸活检组织作为对照。生精上皮受到不同程度的影响，从看似基本正常到严重改变不等。在正常细胞关联受到破坏的小管中，小管上皮的表面解剖结构扭曲，管腔周围支持细胞的细胞质被截断，生殖细胞明显移位、数量减少，在某些极端情况下甚至缺失。通过扫描电子显微镜观察受精索静脉曲张影响的生精上皮，可以更全面地揭示管腔周围区域溶解的程度和三维特征，并再次证实我们对这种病理状态下生精小管的四阶段分类。
