Fukui Y, Smith N T, Fleming R A
Anesth Analg. 1982 Dec;61(12):1010-5.
A control system that maintains mean arterial pressure (MAP) at a desired level by automatically controlling halothane input has been developed. The control system is a discrete, digital type and is implemented with a small desk-top programmable calculator. Essentially, if MAP decreases, the inspired concentration of halothane will decrease; if MAP increases, the system will compensate by increasing inspired halothane concentration. The control system was tested in two ways: with a hybrid computer model of uptake and distribution of halothane and with dog experiments. The results indicate that (a) the model can be used to predict the response of the animal-anesthesia machine control system, and (b) the proposed algorithm is successful in controlling one anesthetic agent with one physiologic variable.
已经开发出一种控制系统，该系统通过自动控制氟烷输入将平均动脉压（MAP）维持在所需水平。该控制系统是离散数字型的，用一台小型台式可编程计算器实现。本质上，如果MAP降低，氟烷的吸入浓度将降低；如果MAP升高，系统将通过增加氟烷吸入浓度进行补偿。该控制系统通过两种方式进行测试：使用氟烷摄取和分布的混合计算机模型以及犬实验。结果表明：（a）该模型可用于预测动物麻醉机控制系统的反应，（b）所提出的算法成功地用一个生理变量控制一种麻醉剂。
