Kraemer M J, Kendall R, Hickman R O, Haas J E, Bierman C W
Ann Allergy. 1982 Dec;49(6):323-5.
A severe generalized multisystem allergic reaction occurred in a 16-month-old infant following the use of trimethoprim-sulfamethoxazole. Acute interstitial nephritis developed three weeks following the onset of this reaction and resolved after three months. This is the first description of this renal toxicity with TMP-SMX in a child.
一名16个月大的婴儿在使用甲氧苄啶-磺胺甲恶唑后发生了严重的全身性多系统过敏反应。该反应发生三周后出现急性间质性肾炎,并在三个月后痊愈。这是首次描述儿童使用甲氧苄啶-磺胺甲恶唑出现这种肾毒性。