Dyer R S, Swartzwelder H S
Pharmacol Biochem Behav. 1978 Sep;9(3):301-6. doi: 10.1016/0091-3057(78)90289-7.
Visually evoked potentials were recorded n male and female rats from albino and hooded strains. Recordings were made at 4 different flash intensities in unanesthetized animals. Clear sex and strain differences were observed. Females had larger amplitude P1-N1 and N1-P2 components and shorter latency N1 peaks than males. Albino rats had larger amplitude P1-N1, N2-Pe and P3-N3 components and longer latency P2 and P3 peaks than hooded rats. Variations in flash intensity produced greater alterations in latencies and N1-P2 amplitudes in hooded rats than in albino rats, but greater alterations in N1, N2 and P3 latencies in albino rats than in hooded rats. Hooded rats are recommended as more valuable for studies of chemically induced change in the visual evoked potential.
在雄性和雌性大鼠中记录了来自白化病和带帽品系的视觉诱发电位。在未麻醉的动物中，于4种不同的闪光强度下进行记录。观察到明显的性别和品系差异。雌性大鼠的P1-N1和N1-P2成分振幅更大，N1峰潜伏期比雄性大鼠短。白化病大鼠的P1-N1、N2-Pe和P3-N3成分振幅更大，P2和P3峰潜伏期比带帽大鼠长。闪光强度的变化在带帽大鼠中比在白化病大鼠中引起的潜伏期和N1-P2振幅变化更大，但在白化病大鼠中比在带帽大鼠中引起的N1、N2和P3潜伏期变化更大。推荐使用带帽大鼠用于化学诱导视觉诱发电位变化的研究，因其更具价值。
