Dyer R S, Eccles U, Swartzwelder H S, Fechter L D, Annau Z
J Environ Sci Health C. 1979;13(2):107-20.
Hooded rats prenatally exposed to mild carbon monoxide hypoxia were studied as adults. Flash evoked potentials were recorded from the visual cortex of unanesthetized exposed and control rats at four different flash intensities. The amplitude of bothe the P1-N1 and N1-P2 components on the flash evoked potential were significantly greater in CO-exposed female rats than in control females. The experiments thus demonstrate long term alterations in CNS function from exposure to relatively mild levels of CO.
对出生前暴露于轻度一氧化碳性缺氧环境的长爪沙鼠成年后进行了研究。在四种不同的闪光强度下，从未麻醉的暴露组和对照组大鼠的视觉皮层记录闪光诱发电位。暴露于一氧化碳的雌性大鼠的闪光诱发电位上P1-N1和N1-P2成分的幅度均显著大于对照雌性大鼠。因此，这些实验证明了暴露于相对轻度的一氧化碳水平会导致中枢神经系统功能的长期改变。
