Boulley A M, Imbert M C, Dehan M, Hernandorena X, Ropert J C, Vial M, Gabilan J C
Arch Fr Pediatr. 1982 Aug-Sep;39(7):423-8.
17 neonates presenting with bilateral hypoplasia of the lungs are reported. Histologic examination of the 13 neonates who died before the 24th hour of life showed 2 histologic types: a "fetal" type, similar to the pulmonary histology of 16-20 weeks fetuses, and a "miniature" type, with reduced dimensions, of harmonious aspect. The association of pulmonary hypoplasia with other fetal malformations suggests a different pathophysiologic mechanism for each type. Recovery may be possible in children with the "miniature" type.
报告了17例出现双侧肺发育不全的新生儿。对13例在出生后24小时内死亡的新生儿进行组织学检查,发现有2种组织学类型:一种是“胎儿型”,类似于16 - 20周胎儿的肺组织学表现;另一种是“微型”,尺寸减小,外观协调。肺发育不全与其他胎儿畸形的关联提示每种类型存在不同的病理生理机制。“微型”类型的儿童可能会康复。