噻嘧啶与左旋咪唑治疗蛔虫和钩虫感染的流行病学研究及比较
Epidemiological study and comparison of pyrantel and levamisole in the treatment of roundworm and hookworm infestations.
作者信息
Huq F, Hamid A A, Ali S, Asaduzzaman M, Yasmin M
出版信息
Bangladesh Med Res Counc Bull. 1982 Jun;8(1):1-6.
Stool examined for presence of nematodes from 467 school students in Dacca city showed 48% ova positive cases with 22% among them cases of mixed nematode infection. Highest prevalence of 58% was observed with roundworm and 5% was hookworm infestations. Among hookworm cases, Necator americana (68%) appears to be the predominant species. Two anthelmintics-pyrantel and levamisole achieved similar high cure rate (around 97%) and Egg reduction rate of 99% in roundworm infection. However, pyrantel was observed to be more effective in hookworm infestation (87% against 60%) particularly in Necator americana cases.
对达卡市467名学生的粪便进行线虫检查，结果显示48%的病例有虫卵阳性，其中22%为混合线虫感染病例。蛔虫感染率最高，为58%，钩虫感染率为5%。在钩虫病例中，美洲板口线虫（68%）似乎是主要种类。两种驱虫药——噻嘧啶和左旋咪唑在蛔虫感染中治愈率相似（约97%），虫卵减少率为99%。然而，观察发现噻嘧啶对钩虫感染更有效（87%对60%），特别是在美洲板口线虫病例中。
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