Regulation of hepatic betaine-homocysteine methyltransferase by dietary methionine.

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作者信息

Finkelstein J D, Harris B J, Martin J J, Kyle W E

出版信息

Biochem Biophys Res Commun. 1982 Sep 16;108(1):344-8. doi: 10.1016/0006-291x(82)91872-1.

DOI:10.1016/0006-291x(82)91872-1

PMID:7150291

Abstract

摘要

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Regulation of hepatic betaine-homocysteine methyltransferase by dietary methionine.

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Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.在大鼠中抑制甜菜碱同型半胱氨酸 S-甲基转移酶会导致高同型半胱氨酸血症，并降低肝脏胱硫醚 β-合酶活性和甲基化能力。

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Active-site-mutagenesis study of rat liver betaine-homocysteine S-methyltransferase.大鼠肝脏甜菜碱-同型半胱氨酸S-甲基转移酶的活性位点诱变研究

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