THE action of ricin A-chain on ribosomes.

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作者信息

MacConnell W P, Eurman D W, Kaplan N O

出版信息

Biochem Biophys Res Commun. 1982 Sep 30;108(2):809-14. doi: 10.1016/0006-291x(82)90901-9.

DOI:10.1016/0006-291x(82)90901-9

PMID:7150325

Abstract

摘要

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THE action of ricin A-chain on ribosomes.

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The specific binding of ricin and its polypeptide chains to rat liver ribosomes and ribosomal subunits.蓖麻毒素及其多肽链与大鼠肝脏核糖体及核糖体亚基的特异性结合。

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Real-time kinetic analyses of the interaction of ricin toxin A-chain with ribosomes prove a conformational change involved in complex formation.蓖麻毒素A链与核糖体相互作用的实时动力学分析证明了复合物形成过程中涉及的构象变化。

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Ribosomal core-particles as the target of ricin.核糖体核心颗粒作为蓖麻毒素的靶点。

Biochem J. 1981 Mar 15;194(3):1015-7. doi: 10.1042/bj1941015.

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