[Effects on the process of DNA transcription in vitro of formaldehyde and the products of its reaction with amines].
作者信息
Protasova I A, Semin Iu A, Adler V V, Poverennyĭ A M
出版信息
Biokhimiia. 1982 Nov;47(11):1778-84.
PMID:7150669
Abstract
When transcription of DNA treated with aminomethylol compounds (products of formaldehyde reaction with amines) was studied, aminomethylol produced a marked inhibition of the template activity of double-stranded DNA (up to 85%). Formaldehyde suppressed the transcription of native DNA as well, however, only when taken at concentrations exceeding those of the aminomethylol compounds 20-fold.
摘要
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