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[Catecholamines in the myocardium of growing rats after pharmacological sympathectomy].

作者信息

Viktorov A P, Zasenko I I

出版信息

Farmakol Toksikol. 1982 Nov-Dec;45(6):38-41.

PMID:7151997
Abstract

Examination of the myocardium of 7-, 30-day and 3--5-month-old rats has shown that the content of noradrenaline and adrenaline increased with age. The sympatholytics, reserpine and ornid diminished more markedly the content of catecholamines in the myocardium of 7- and 30-day-old animals. Dopegyt produced a greater catecholamine-reducing effect in 3--5-month-old animals. It is inferred that in the early postnatal ontogenesis, the myocardial response to the sympatholytics is determined by age-associated features of adrenergic control and metabolism.

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