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[抗交感神经药和β-肾上腺素能阻滞剂对生长中大鼠心肌碳水化合物-磷代谢指标影响的比较评估]

[Comparative assessment of the effect of sympatholytics and beta-adrenoblockaders on carbohydrate-phosphorus metabolic indices in the myocardium of growing rats].

作者信息

Viktorov A P, Chekman I S

出版信息

Farmakol Toksikol. 1978 Mar-Apr;41(2):168-71.

PMID:26589
Abstract

The sympatholyitic ornide and beta-adrenoblocking agent alpheprol were introduced intraperitoneally in single doses of 5 and 1 mg/kg, respectively to 7--30 day and 3--5-month old adult rats. The content of ATP, ADP, AMP, inorganic phosphorus glycogen and also active P32 incorporation were determined. The 7-day old rattlings are shown to be more sensitive to ornide than to alpheprol by comparison with older animals.

摘要

将抗交感神经药奥尼德和β-肾上腺素能阻滞剂阿普洛尔分别以5毫克/千克和1毫克/千克的单次剂量腹腔注射给7至30日龄和3至5月龄的成年大鼠。测定了三磷酸腺苷（ATP）、二磷酸腺苷（ADP）、一磷酸腺苷（AMP）、无机磷、糖原的含量以及活性磷32的掺入情况。与年长动物相比，7日龄的幼鼠对奥尼德比对阿普洛尔更敏感。

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1
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