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鼻腔嗜酸性粒细胞和肥大细胞在有鼻部症状儿童中的意义。

The significance of nasal eosinophils and mast cells in children with nasal symptoms.

作者信息

Kemp A S, Simpson J, Mellis C M

出版信息

Int J Pediatr Otorhinolaryngol. 1982 Oct;4(4):293-9. doi: 10.1016/0165-5876(82)90041-6.

DOI:10.1016/0165-5876(82)90041-6
PMID:7152841
Abstract

Nasal smears from children with symptoms of nasal obstruction and/or discharge were examined for the presence of eosinophils, mucus-containing cells and mast cells. The presence of more than one eosinophil or any mast cells was significantly associated with atopy as determined by immediate hypersensitivity on skin prick testing. Twelve children with markedly increased numbers of nasal smear mast cells are described. In these children symptoms frequently commenced in the first 6 months of life. Nasal eosinophilia was not noted in any of the cases. Nasal smear mastocytosis was associated with significant perennial symptoms and would be missed if nasal smears are examined only for eosinophilia.

摘要

对有鼻塞和/或流涕症状的儿童进行鼻涂片检查,以确定是否存在嗜酸性粒细胞、含黏液细胞和肥大细胞。通过皮肤点刺试验的速发型超敏反应确定,鼻涂片中嗜酸性粒细胞超过一个或存在任何肥大细胞与特应性显著相关。本文描述了12例鼻涂片肥大细胞数量明显增加的儿童。在这些儿童中,症状通常在出生后的前6个月开始出现。所有病例均未发现鼻嗜酸性粒细胞增多。鼻涂片肥大细胞增多症与明显的常年性症状相关,如果仅检查鼻涂片的嗜酸性粒细胞增多情况,可能会漏诊。

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