Vik-Mo H
Scand J Haematol. 1978 Sep;21(3):225-32. doi: 10.1111/j.1600-0609.1978.tb00357.x.
The distribution of labelled autologous platelets in the myocardium was studied in open-chest dogs following a nonthrombotic coronary artery occlusion. A significant accumulation of platelets occurred in the ischaemic and borderline ischaemic myocardium both 15 and 150 min after coronary artery occlusion, most pronounced after 150 min. The small platelet accumulation after 15-min ischaemia might be due to stasis of blood since a similar increase in labelled erythrocytes in that area was observed. The platelet trapping after 150 min most likely represents platelet aggregates. In spite of the marked increase in platelet trapping, the myocardial blood flow in the ischaemic area increased significantly from 15 to 150 min of myocardial ischaemia. It is concluded that the increased platelet trapping in the first hours following a nonthrombotic coronary artery occlusion was insufficient to impair coronary circulation.
在开胸犬非血栓性冠状动脉闭塞后，研究了标记的自体血小板在心肌中的分布情况。冠状动脉闭塞后15分钟和150分钟，缺血和边缘缺血心肌中均出现血小板显著聚集，150分钟后最为明显。15分钟缺血后血小板少量聚集可能是由于血液淤滞，因为在该区域观察到标记红细胞有类似增加。150分钟后血小板滞留很可能代表血小板聚集物。尽管血小板滞留显著增加，但从心肌缺血15分钟到150分钟，缺血区域的心肌血流量仍显著增加。结论是非血栓性冠状动脉闭塞后的最初数小时内，血小板滞留增加不足以损害冠状动脉循环。
