Grüntzig A, Hirzel H, Goebel N, Gattiker R, Turina M, Myler R, Stertzer S, Kaltenbach M
Schweiz Med Wochenschr. 1978 Nov 4;108(44):1721-3.
The technique of percutaneous transluminal dilatation of coronary artery stenosis consists of a catheter system introduced via the femoral artery under local anesthesia. A preshaped guiding catheter is positioned in the orifice of the coronary artery and through this a dilatation catheter is inserted into the branches if the artery. This dilatation catheter (outer diameter 0.5--1.25 mm) is equipped with a sausage-shaped distensible segment (balloon) at the tip. The balloon is inflated to a pressure of 5 atm. This pressure compresses the atherosclerotic material in a direction perpendicular to the wall of the vessel, therby dilating the lumen. Up to now 29 patients have been treated with primary success in 23 (79%) and long-lasting success in 21 (72%). Three patients underwent emergency coronary surgery to avoid infarction. Dilatation is indicated in patients with disabling angina which jeopardizes their quality of life and with coronary lesions which are proximal, subtotal, concentric and non-calcified.
冠状动脉狭窄经皮腔内扩张技术是在局部麻醉下通过股动脉插入导管系统。一根预塑形的引导导管置于冠状动脉口，通过它将一根扩张导管插入动脉分支。这种扩张导管（外径0.5 - 1.25毫米）尖端装有一个香肠形可扩张节段（球囊）。球囊充气压至5个大气压。此压力将动脉粥样硬化物质沿垂直于血管壁的方向压缩，从而扩张管腔。到目前为止，29例患者接受了治疗，23例（79%）获得初步成功，21例（72%）获得长期成功。3例患者接受了急诊冠状动脉手术以避免梗死。对于有严重心绞痛且危及生活质量的患者以及冠状动脉病变位于近端、次全、同心且无钙化的患者，可进行扩张治疗。
