Ivanova N A, Grinbaum E B, Taros L Iu, Luzianina T Ia, Smorodintsev A A
Vopr Virusol. 1982 Nov-Dec;27(6):667-71.
Examinations by the HI test of 652 sera from children aged from 9 months to 13 years revealed antibodies to A/Singapore/1/57 (H2N2) in 0.9% and A/PR/8/34 (H0N1) in 1.2% of the children. The specific nature of the activity of the sera was proved by neutralization tests and by treatment of the sera with Staphylococcus aureus adsorbing IgG class antibodies. Antineuraminidase antibodies to these viruses were also detected. Examinations of 247 paired sera from children revealed seroconversion to hemagglutinin and neuraminidase of A/Singapore/1/57 and A/PR/8/34 in 2% and 0.4%, respectively. These results testify to continuing circulation in the human population of influenza A virus subtypes of no current epidemiological importance.
对652份9个月至13岁儿童血清进行血凝抑制试验检测发现，0.9%的儿童体内有针对A/新加坡/1/57（H2N2）的抗体，1.2%的儿童体内有针对A/PR/8/34（H0N1）的抗体。通过中和试验以及用金黄色葡萄球菌吸附IgG类抗体处理血清，证实了血清活性的特异性。还检测到针对这些病毒的抗神经氨酸酶抗体。对247份儿童配对血清进行检测发现，分别有2%和0.4%的儿童血清转化为针对A/新加坡/1/57和A/PR/8/34的血凝素和神经氨酸酶。这些结果证明，目前不具有流行病学重要性的甲型流感病毒亚型仍在人群中传播。
