Arendt A
Zentralbl Allg Pathol. 1982;126(5-6):499-504.
The histological structure of gliomas and their relapses is an expression of the biological behaviour and thus permits certain prognostic statements. Especially astrocytomas show a tendency to progressive dedifferentiation. In oligodendrogliomas there is a slight tendency to dedifferentiation and in ependymomas it is very seldom. Recurrent pilocytic astrocytomas are without dedifferentiation in our material. The change in the histological features found in many gliomas on the examination of relapses is to be considered as an expression of changed biological activity.
胶质瘤及其复发的组织学结构是生物学行为的一种表现,因此可以做出某些预后判断。特别是星形细胞瘤呈现出进行性去分化的趋势。少突胶质细胞瘤有轻微的去分化倾向,而室管膜瘤则很少见。在我们的病例材料中,复发性毛细胞型星形细胞瘤没有去分化现象。在许多胶质瘤复发检查中发现的组织学特征变化应被视为生物学活性改变的一种表现。