蛋白质在体外吸附到覆盖有ULTI碳的生物材料表面。

Protein adsorption in vitro onto biomaterial surfaces covered with ULTI carbon.

作者信息

Borovetz H S, Molek G E, Levine G, Hardesty R L, Haubold A D

出版信息

Biomater Med Devices Artif Organs. 1982;10(3):187-203. doi: 10.3109/10731198209118780.

DOI:10.3109/10731198209118780

Abstract

A study is presented which describes the adsorption in vitro of albumin and fibrinogen onto a mini-shunt oxygenation unit. The unit is characterized by flow through 10 etched microchannel conduits with a microporous membrane and conduits are pretreated with a uniform layer of ULTI carbon and evaluated for the steady-state and time varying kinetics of protein adsorption. Corresponding results for oxygenator components not pretreated with ULTI carbon are also included.

摘要

本文介绍了一项关于白蛋白和纤维蛋白原在微型分流氧合装置上的体外吸附研究。该装置的特点是通过10个带有微孔膜的蚀刻微通道导管进行流动，导管用均匀的ULTI碳层进行预处理，并对蛋白质吸附的稳态和随时间变化的动力学进行评估。还包括未用ULTI碳预处理的氧合器组件的相应结果。