Velcek F T, Jongco B, Shaftan G W, Klotz D H, Rao S P, Schiffman G, Kottmeier P K
J Pediatr Surg. 1982 Dec;17(6):879-83. doi: 10.1016/s0022-3468(82)80460-0.
Previous work in our laboratories showed that canine omental replantation of splenic wafers leads to reproducible viability, restoration of filtrative function, bacterial clearance, and normal antibody formation. An identical technique has been employed in children whose spleen could not be repaired since 1979. During a 3-yr follow-up viability of the replanted segments was documented with return of filtrative function, normal immunoglobulin, and antibody response. Splenic preservation through operative repair or selective nonoperative observation should remain the primary goal after splenic trauma. If this is not possible, splenic replantation represents an alternative approach in the treatment of splenic trauma.
我们实验室之前的研究表明,将脾脏薄片移植到大网膜上可使犬类实现可重复的存活、滤过功能恢复、细菌清除以及正常抗体形成。自1979年以来,相同的技术已应用于脾脏无法修复的儿童。在3年的随访中,记录了移植片段的存活情况,包括滤过功能恢复、免疫球蛋白正常化和抗体反应。脾脏创伤后,通过手术修复或选择性非手术观察来保留脾脏应始终是首要目标。如果无法做到这一点,脾脏移植是治疗脾脏创伤的一种替代方法。