Denko C W, Aponte J, Gabriel P, Petricevic M
J Rheumatol. 1982 Nov-Dec;9(6):827-33.
Serum beta-endorphin levels have been determined in patients with a wide variety of rheumatic disorders as well as a group of healthy men and women controls. Normal levels of endorphin have been found in patients with juvenile rheumatoid arthritis. Patients with rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, gout, ankylosing spondylitis, pseudogout and psoriatic arthritis have diminished levels of endorphins. Speculation is offered to explain these changes. Perturbations in endorphins are postulated to be part of the organism's protective mechanism in inflammatory arthritis.
已经测定了患有各种风湿性疾病的患者以及一组健康男性和女性对照者的血清β-内啡肽水平。在青少年类风湿性关节炎患者中发现内啡肽水平正常。类风湿性关节炎、骨关节炎、系统性红斑狼疮、痛风、强直性脊柱炎、假性痛风和银屑病关节炎患者的内啡肽水平降低。文中提供了推测来解释这些变化。内啡肽的紊乱被假定为炎症性关节炎中机体保护机制的一部分。
