Tesić M, Segedi D, Ziramov J
Jugosl Ginekol Opstet. 1982 May-Aug;22(3-4):67-70.
The authors present 11 patients with ovarian dysgerminoma treated at the Institute of Oncology and the University Hospital Department of Gynecology and Obstetrics in Novi Sad. The average age of the patients was 33.90 years (the mean value 27). In most of them the disease was in an advanced stage, with considerable local findings at the beginning of the treatment. In only three 3 patients was the disease relatively limited. The results of the treatment were unsatisfactory: three patients have been alive for 8, 11, and 12 years after the beginning of the treatment, three patients after 6 and 26 months and are still under treatment but with suspect clinical or laboratory findings, whereas the remaining five died in the period between 3 and 4 months following the beginning of the treatment. All these patients were treated surgically in the first place, but radiotherapy proved of great help, because this tumour is markedly radiosensitive, and also chemotherapy was useful in some of the women treated. In general, therapy should be strictly adjusted to individual cases, primarily because the disease appears more frequently in younger women.
作者介绍了在诺维萨德肿瘤研究所及大学医院妇产科接受治疗的11例卵巢无性细胞瘤患者。患者的平均年龄为33.90岁(均值为27岁)。大多数患者疾病处于晚期,治疗开始时局部表现明显。只有3例患者疾病相对局限。治疗结果不尽人意:3例患者在治疗开始后存活了8年、11年和12年,3例患者分别在6个月和26个月后仍在接受治疗,但临床或实验室检查结果可疑,而其余5例在治疗开始后的3至4个月内死亡。所有这些患者首先接受了手术治疗,但放疗被证明有很大帮助,因为这种肿瘤对放疗明显敏感,化疗对部分接受治疗的女性也有用。总体而言,治疗应严格根据个体情况进行调整,主要是因为该疾病在年轻女性中更常见。