Scragg R K, Dorsch M M, McMichael A J, Baghurst P A
Med J Aust. 1982;2(12):577-9. doi: 10.5694/j.1326-5377.1982.tb132578.x.
We report a descriptive study indicating a localised excess of congenital malformations in Mount Gambier, South Australia, and summary results of a subsequent case-control study showing an association between the occurrence of congenital malformations and the consumption of underground water by pregnant women. The internal cohesion of the data analyses, and the plausibility conferred by experimental evidence, suggests that the underground water, and its elevated concentration of nitrates, may warrant further consideration as a source of human teratogens.
我们报告了一项描述性研究，该研究表明南澳大利亚州甘比尔山存在先天性畸形的局部过量情况，以及随后一项病例对照研究的总结结果，该结果显示先天性畸形的发生与孕妇饮用地下水之间存在关联。数据分析的内在一致性以及实验证据所赋予的合理性表明，地下水及其升高的硝酸盐浓度可能值得进一步作为人类致畸物来源加以考虑。
