Rossen B, Ladefoged J
Scand J Urol Nephrol. 1982;16(3):279-81. doi: 10.3109/00365598209179767.
A comparison was carried out regarding peritoneal dialysis using acetate in preference to lactate as the buffer anion in the dialysis solution. The investigation was made with 5 patients on long-term peritoneal dialysis once a week, first for 5 weeks with dialysis solution containing acetate and then, correspondingly, 5 dialyses with peritoneal solution containing lactate. A tendency to a slightly higher standard bicarbonate level at the end of dialysis was found when using the solution containing acetate. Furthermore, it appeared that total calcium and ionized calcium values were higher at the end of dialysis with the solution containing lactate. The latter may be ascribed to a difference in the degree of chelate binding of calcium in the two solutions. There were no differences in hemoglobin, s-sodium, s-potassium, s-urea, s-creatinine, s-phosphate and blood pressure values before and after dialysis with the two solutions. It is concluded that lactate scarcely offers any advantages in preference to acetate in peritoneal dialysis.
对使用醋酸盐而非乳酸盐作为透析液缓冲阴离子的腹膜透析进行了比较。对5名每周进行一次长期腹膜透析的患者进行了研究，首先使用含醋酸盐的透析液进行5周透析，然后相应地使用含乳酸盐的腹膜透析液进行5次透析。使用含醋酸盐的透析液时，在透析结束时发现标准碳酸氢盐水平有略高的趋势。此外，含乳酸盐的透析液在透析结束时总钙和离子钙值似乎更高。后者可能归因于两种溶液中钙的螯合结合程度不同。两种溶液透析前后血红蛋白、血清钠、血清钾、血清尿素、血清肌酐、血清磷酸盐和血压值均无差异。得出的结论是，在腹膜透析中，乳酸盐几乎没有比醋酸盐更具优势。
