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[50岁以上肺结核患者经超声雾化吸入给药后血液中链霉素和异烟肼的浓度]

[Concentration of streptomycin and isoniazid in the blood of patients over 50 with pulmonary tuberculosis after administration of the drugs in ultrasonic aerosols].

作者信息

Korablev V N

出版信息

Antibiotiki. 1982 Dec;27(12):53-6.

PMID:7165296
Abstract

Patients aged over 50 with pulmonary tuberculosis were treated with streptomycin and isoniazid administered by the routine routes and in the form of ultrasound aerosols. The drug levels in the blood of the patients were studied comparatively. It was shown that administration of the drugs in the form of aerosols provided their sufficiently high blood levels for a long time in patients with a primary diagnosis of the disease. Such levels did not depend on the patients' age and the state of the lung ventilation.

摘要

对50岁以上的肺结核患者采用常规途径并以超声雾化形式给予链霉素和异烟肼进行治疗。对患者血液中的药物水平进行了比较研究。结果表明,对于初诊为此病的患者,以雾化形式给药可使药物在血液中长时间保持足够高的水平。这些水平与患者的年龄和肺通气状态无关。

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