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[锇酸滑膜切除术在血友病性关节病治疗中的重要性。附19例报告]

[Importance of synoviorthesis using osmic acid in the treatment of hemophilic arthropathy. Apropos of 19 cases].

作者信息

Bardier M, Gayraud J P, Robert A, Thillaye du Boullay L, Dirat G, Boneu B, Durroux R, Bierme R, Regnier C, Gaubert J

出版信息

Chir Pediatr. 1982;23(6):393-9.

PMID:7165889
Abstract

While getting synovial sclerosis and articular drying, the synoviorthesis breaks the circulus vicious which comes from iterative hemarthrosis to articular destruction. With 25 cases and a follow up of 6 years, we have got 39% of good results, 35% of medium and 26% of bad ones. The therapeutic efficiency requires a certain latent time (0 to 15 days for isotopical synoviorthesis, 2 to 3 months for those ones with osmical acid.) A new synoviorthesis can be made if needed. Neither age nor radiological stage are of any influence. The radiological worsening uses to go on unchanged. The synoviorthesis should be performed at an early stage, previous to the cartilage and bone destructions.

摘要

在发生滑膜硬化和关节干燥时,滑膜切除术打破了从反复关节积血到关节破坏的恶性循环。对25例患者进行了6年的随访,结果显示,良好率为39%,中等率为35%,差的为26%。治疗效果需要一定的潜伏期(同位素滑膜切除术为0至15天,使用锇酸的为2至3个月)。如有需要可进行再次滑膜切除术。年龄和放射学分期均无影响。放射学恶化通常保持不变。滑膜切除术应在软骨和骨破坏之前的早期进行。

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