Speer D P
Hip. 1982:68-88.
The several anatomic features that permit the growth plate to resist shear forces were identified. Specific variations in these anatomic features were correlated with pathologic factors known to be associated with epiphysiolysis, including clinical correlations with slipped capital femoral epiphysis. Two models of epiphysiolysis representing different pathogenetic pathways were established in the pig and compared to clinical slipped capital femoral epiphysis in the human. Both experimental models and other models reported in the literature bear similarities mechanically and histologically to the human disease. Available evidence suggests that slipped capital femoral epiphysis may not be a single disease but a final mechanical event that occurs as a result of a variety of disease processes. These disease processes reduce by different mechanisms the ability of the growth plate to resist shear forces.
确定了允许生长板抵抗剪切力的几个解剖学特征。这些解剖学特征的特定变化与已知与骺板溶解相关的病理因素相关，包括与股骨头骨骺滑脱的临床相关性。在猪身上建立了代表不同发病机制的两种骺板溶解模型，并与人类临床股骨头骨骺滑脱进行了比较。实验模型和文献中报道的其他模型在机械和组织学上都与人类疾病相似。现有证据表明，股骨头骨骺滑脱可能不是单一疾病，而是由多种疾病过程导致的最终机械事件。这些疾病过程通过不同机制降低了生长板抵抗剪切力的能力。
