Reynaud P, Kohler R
Service de Chirurgie et Orthopédie pédiatrique, Hôpital Edouard Herriot, Lyon.
Rev Chir Orthop Reparatrice Appar Mot. 1996;82(1):76-79.
The authors report two cases of children treated with growth hormone who had a secondary slipped capital femoral epiphysis. Endocrine disease, radiotherapy are some well-known etiological factors reported in literature, but growth hormone influence is still discussed. This hormone could have an indirect incidence on this pathology because of its effects on growth cartilage. The increased number of treatment with growth hormone is certainly a risk factor for slipped capital femoral epiphysis. Regular checking from "France Hypophyse" allows an early diagnosis of epiphysis and surgical fixation can be made immediately. Systematic controlateral side fixation it still discussed but allowed to continue the treatment with the same posology.
作者报告了两例接受生长激素治疗的儿童发生继发性股骨头骨骺滑脱的病例。内分泌疾病、放射治疗是文献中报道的一些已知病因，但生长激素的影响仍在讨论中。由于其对生长软骨的作用，这种激素可能对该病理状况有间接影响。生长激素治疗次数的增加肯定是股骨头骨骺滑脱的一个危险因素。来自“法国垂体协会”的定期检查可实现骨骺的早期诊断，并且可以立即进行手术固定。对于是否进行系统性对侧固定仍在讨论中，但允许以相同剂量继续治疗。
