Irkeç C, Irkeç M
Mikrobiyol Bul. 1982 Jul;16(3):191-5.
Uremia is a metabolic imbalance accompanied by an acquired immunologic deficiency state. Fatal infections frequently met with uremia may be explained both by cellular and humoral immunologic disorders. In this article, the cellular immune status was investigated via intradermal skin test, and the serum and cerebrospinal fluid (CSF) immunoglobulins were detected. Results indicated that a cellular and humoral immunologic deficiency, which deteriorated in accordance with the clinical status, existed and a CSF immunoglobulin increase, presumably due to changes in the blood - CSF barrier, was noted.
尿毒症是一种伴有获得性免疫缺陷状态的代谢失衡。尿毒症患者经常遭遇的致命感染可通过细胞和体液免疫紊乱来解释。在本文中，通过皮内皮肤试验研究细胞免疫状态，并检测血清和脑脊液（CSF）免疫球蛋白。结果表明，存在细胞和体液免疫缺陷，且其随临床状态恶化，还注意到脑脊液免疫球蛋白增加，这可能是由于血脑屏障的变化所致。
