Lee H P, Cuello C, Singh K
Natl Cancer Inst Monogr. 1982;62:197-9.
Cervical cancer, despite its declining incidence in the developed countries, is still an important cancer in the less-developed world. The mortality and incidence trends for some of the countries in the Pacific Basin are presented. Among the high-risk communities and populations are Colombia (Cali), New Zealand (Maoris), El Paso, Texas (Latin Americans), California (blacks), Hawaii (Hawaiians), Singapore (Chinese and Indians), Hong Kong, Philippines (Manila), New Caledonia (Melanesians), Alaska (American Indians), Fiji. The major risk factors are summarized, with age at first coitus as the key factor; some doubts are expressed about the validity of multiple sexual partners and circumcision of male partners as risk factors. The likely role of herpesvirus is still being studied, and the possible increase in incidence of cervical cancer among younger women could be attributed to greater sexual promiscuity in that group. Some suggestions for future research are made.
宫颈癌,尽管在发达国家其发病率呈下降趋势,但在欠发达国家仍是一种重要的癌症。文中呈现了太平洋盆地一些国家的死亡率和发病率趋势。高风险社区和人群包括哥伦比亚(卡利)、新西兰(毛利人)、得克萨斯州埃尔帕索(拉丁美洲人)、加利福尼亚(黑人)、夏威夷(夏威夷人)、新加坡(华人和印度人)、香港、菲律宾(马尼拉)、新喀里多尼亚(美拉尼西亚人)、阿拉斯加(美洲印第安人)、斐济。总结了主要风险因素,首次性交年龄是关键因素;对多个性伴侣和男性伴侣包皮环切作为风险因素的有效性表示了一些怀疑。疱疹病毒的可能作用仍在研究中,年轻女性宫颈癌发病率可能增加可归因于该群体中更滥交的性行为。提出了一些未来研究的建议。