Buczko W, Lukaszyk A, Wiśniewski K
Pol J Pharmacol Pharm. 1982;34(1-3):101-6.
The reactivity of the central nervous system in the disseminated intravascular coagulation was studied. In this state the action of pentylenetetrazol and thiopental were decreased. Also shortening of tonic phase of electric convulsions was observed. No changes were noted in the contents of noradrenaline and serotonin, whereas slight increase in dopamine level in some regions of brain was found. It seems that observed effects are connected with other mechanisms than interaction with central mediators.
研究了弥散性血管内凝血时中枢神经系统的反应性。在这种状态下，戊四氮和硫喷妥钠的作用减弱。还观察到电惊厥强直期缩短。去甲肾上腺素和5-羟色胺含量未见变化，而在脑的某些区域多巴胺水平略有升高。看来所观察到的效应与和中枢介质相互作用不同的其他机制有关。
