Gunsett F C, Andriano K N, Rutledge J J
Biometrics. 1982 Dec;38(4):981-9.
The genetic change from multiple-trait selection experiments can be equated to the regression of genotype on phenotype. This gives rise to a method of obtaining estimates of additive genetic variances and covariances. The method requires the use of selection weights, derived by means of the index-in-retrospect, to provide invariant solutions. Solution variance estimates obtained from Monte Carlo simulation do not agree with variance estimates from ordinary least squares methods. This indicates that the errors are distributed with some structure V. A form of V is proposed which utilizes knowledge of the errors. Monte Carlo variance estimates from generalized least squares (GLS) methods agree closely with the average variance estimates from GLS when the proposed V is used. Use of an estimated V, derived after the initial estimation procedure, is shown to provide adequate information on the variance of the estimates.
多性状选择实验中的遗传变化可等同于基因型对表型的回归。这产生了一种获取加性遗传方差和协方差估计值的方法。该方法需要使用通过回顾性指数得出的选择权重来提供不变解。从蒙特卡罗模拟获得的解方差估计值与普通最小二乘法的方差估计值不一致。这表明误差是以某种结构V分布的。提出了一种V的形式,它利用了误差的知识。当使用所提出的V时,广义最小二乘法(GLS)的蒙特卡罗方差估计值与GLS的平均方差估计值非常接近。结果表明,使用在初始估计过程之后得出的估计V能够提供关于估计值方差的充分信息。