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在婴儿猝死综合征“险些发生”事件期间及之后观察和记录到的呼吸和心脏事件。

Respiratory and cardiac events observed and recorded during and following a "near miss" for Sudden Infant Death Syndrome episode.

作者信息

Cornwell A C, Weitzman E D, Kravath R E

出版信息

Int J Neurosci. 1982 May;16(3-4):231-9. doi: 10.3109/00207458209147151.

Abstract

Documented observations of a 5-week-old infant during a "near miss" for a Sudden Infant Death Syndrome (SIDS) episode by a physician were carried out during an in-hospital physiological recording of respiratory and cardiac activity. This "near miss" event occurred during quiet sleep and was characterized by a prolonged apneic attack with marked bradycardia, cyanosis and limpness which required immediate vigorous resuscitative efforts by a physician and trained nurse. Parental descriptions of similar events parallel these documented sudden unexpected changes in cardiorespiratory parameters. Objective polygraphic data were obtained immediately following the episode and at later ages during 24 and 48 hour continuous recordings of respiration, heart rate, sleep/wake and behavioral activity. The data show that numerous apneic episodes occurred following the "near miss" event, many accompanied by marked bradycardia. The moderately severe hypoxemia noted during these sleep-related apneas indicate that immediate intervention is required to prevent significant hypoxia and central depression in such infants.

摘要

一名医生在对一名5周大婴儿进行呼吸和心脏活动的院内生理记录期间,记录了该婴儿在一次婴儿猝死综合征(SIDS)“险些发生”事件中的情况。这次“险些发生”事件发生在安静睡眠期间,其特征为长时间的呼吸暂停发作,并伴有明显的心动过缓、发绀和肢体无力,这需要医生和受过训练的护士立即进行有力的复苏努力。父母对类似事件的描述与这些记录的心肺参数突然意外变化情况相符。在该事件发生后以及之后不同年龄段,在对呼吸、心率、睡眠/觉醒和行为活动进行24小时和48小时连续记录期间,获取了客观的多导睡眠图数据。数据显示,在“险些发生”事件之后出现了大量呼吸暂停发作,许多伴有明显的心动过缓。在这些与睡眠相关的呼吸暂停期间观察到的中度严重低氧血症表明,需要立即进行干预,以防止此类婴儿出现严重缺氧和中枢抑制。

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