Guilleminault C, Ariagno R, Souquet M, Dement W C
Lancet. 1976 Jun 19;1(7973):1326-7. doi: 10.1016/s0140-6736(76)92656-8.
Sleep, respiratory, and cardiac data obtained during sleep and wakefulness by continuous 24-hour polygraphic monitoring from twelve infants who were "near misses" for the sudden-infant-death syndrome were compared with similar information obtained from seven low-risk infants. Although the sleep variables studied were of limited value in differentiating between the low and high risk patients, respiratory and cardiac abnormalities were strikingly more common in near-miss infants. High-risk infants demonstrated both obstructive and mixed stopped-breathing episodes (S.B.E.). Bradycardia was seen secondary to S.B.E. but also simultaneously with or independent of S.B.E. Sudden asystole associated with S.B.E. was seen in one case. These results suggest an autonomic-nervous-system dysfunction in high-risk infants.
通过对12名有婴儿猝死综合征“濒死经历”的婴儿进行连续24小时多导睡眠图监测,获取其睡眠、呼吸和心脏数据,并与7名低风险婴儿的类似信息进行比较。尽管所研究的睡眠变量在区分低风险和高风险患者方面价值有限,但呼吸和心脏异常在濒死经历婴儿中明显更为常见。高风险婴儿表现出阻塞性和混合性呼吸暂停发作(S.B.E.)。心动过缓继发于S.B.E.,但也可与S.B.E.同时出现或独立于S.B.E.出现。有1例出现与S.B.E.相关的突然心脏停搏。这些结果提示高风险婴儿存在自主神经系统功能障碍。