Nishikaze O, Furuya E, Takita H, Inoue N, Imai A
Int J Tissue React. 1982;4(4):261-4.
Inflammation is a biological defence mechanism against noxious stimuli. Over-strong and oversuppressed inflammatory responses both lead to tissue damage and delay of tissue repair. Determination of inflammatory responses on the basis of chemical mediators, however, only informs about the degree of these responses themselves. It cannot show whether these responses are over-strong or oversuppressed. We have developed a prototype standard for safe judgement of the appropriateness of inflammatory responses: measurements of lipid peroxide (a product of tissue damage) and a newly-discovered amidase (related to wound healing).
炎症是一种针对有害刺激的生物防御机制。过度强烈和过度抑制的炎症反应都会导致组织损伤和组织修复延迟。然而，基于化学介质来确定炎症反应，仅能告知这些反应本身的程度，无法表明这些反应是过度强烈还是过度抑制。我们已经开发出一种用于安全判断炎症反应适当性的原型标准：测量脂质过氧化物（组织损伤的一种产物）和一种新发现的酰胺酶（与伤口愈合相关）。
