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汞暴露工人的神经毒性作用。

Neurotoxic effects in mercury-exposed workers.

作者信息

Triebig G, Schaller K H

出版信息

Neurobehav Toxicol Teratol. 1982 Nov-Dec;4(6):717-20.

PMID:7170033
Abstract

Mercury levels in blood and urine and several nerve conduction velocities (CV) were measured in two groups of workers exposed to mercury (Hg) and in a reference group. Furthermore neuropsychiatric examination and psychological tests were performed. There was a significant mild degree of slowing of sensory CV, but no dose-effect relationship was evaluated on a group basis. The individual assessment showed in some cases hints of abnormal CV caused by mercury exposure. Significant correlations were found between duration of exposure and decrease of short-term memory. However there was no relationship in the case of the other psychological tests. In conclusion, results indicate that there are no disorders of central and/or peripheral nervous system function if the valid Biological Threshold Limit Values in FRG (50 micrograms Hg/l blood and/or 200 micrograms Hg/l urine) are not exceeded.

摘要

对两组接触汞(Hg)的工人和一组参照组工人测量了血液和尿液中的汞含量以及几种神经传导速度(CV)。此外,还进行了神经精神病学检查和心理测试。感觉神经传导速度有明显轻度减慢,但未在组水平上评估剂量效应关系。个体评估显示,在某些情况下有汞暴露导致神经传导速度异常的迹象。发现暴露时间与短期记忆减退之间存在显著相关性。然而,在其他心理测试中未发现相关性。总之,结果表明,如果不超过德国的有效生物阈限值(血液中50微克汞/升和/或尿液中200微克汞/升),中枢和/或外周神经系统功能无紊乱。

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引用本文的文献

1
Persistence of mercury-induced motor and sensory neurotoxicity: systematic review of workers previously exposed to mercury vapor.汞诱导的运动和感觉神经毒性的持续性:对既往暴露于汞蒸气的工人的系统评价
Crit Rev Toxicol. 2017 Nov;47(10):845-866. doi: 10.1080/10408444.2017.1342599. Epub 2017 Jul 19.
2
Mercury-induced motor and sensory neurotoxicity: systematic review of workers currently exposed to mercury vapor.汞引起的运动和感觉神经毒性:对当前接触汞蒸气工人的系统评价。
Crit Rev Toxicol. 2017 Nov;47(10):811-844. doi: 10.1080/10408444.2017.1342598. Epub 2017 Jul 18.
3
[Neurotoxicity of chemical substances in the workplace. VI. Longitudinal study of persons occupationally exposed to mercury].
[工作场所化学物质的神经毒性。VI. 职业性接触汞人员的纵向研究]
Int Arch Occup Environ Health. 1984;55(1):19-31. doi: 10.1007/BF00378064.
4
Differences in frequency of finger tremor in otherwise asymptomatic mercury workers.无症状汞作业工人手指震颤频率的差异。
Br J Ind Med. 1990 Dec;47(12):838-43. doi: 10.1136/oem.47.12.838.
5
Effects of occupational exposure to mercury vapour on the central nervous system.职业性接触汞蒸气对中枢神经系统的影响。
Br J Ind Med. 1992 Aug;49(8):545-55. doi: 10.1136/oem.49.8.545.